Name: UTP-αS
Brand: BOC Sciences
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UTP-αS

UTP-αS is a modified form of uridine triphosphate (UTP). In UTP-αS, the oxygen atom in the α-phosphate group of UTP is replaced by a sulfur atom, creating a non-hydrolyzable analog of UTP. This modification allows UTP-αS to mimic the structure of UTP while preventing its hydrolysis. UTP-αS is commonly utilized in biochemical and molecular biology research to study UTP-dependent processes, such as RNA synthesis, RNA editing, and other nucleic acid-related functions.

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Catalog

BRP-00449

Synonyms

Alpha Thiol UTP; 1-Thio-UTP; Uridine-5'-O-(1-Thiotriphosphate); Uridine, 5'→P''-ester with thiotriphosphoric acid; Thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(S)(OH)2), 5'-monoester with uridine; UTPαS

CAS

18875-71-3

IUPAC Name

[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate

Molecular Weight

500.21

Molecular Formula

C9H15N2O14P3S

SMILES

C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=S)(O)OP(=O)(O)OP(=O)(O)O)O)O

InChI

InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(23-8)3-22-28(21,29)25-27(19,20)24-26(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,29)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-,28?/m1/s1

InChIKey

BWPNYQWDXHLOGU-NOUWQNLYSA-N

Purity

≥95% by HPLC

Density

2.030±0.06 g/cm3

Appearance

Colorless to slightly yellow liquid

Storage

Store at -20 °C

Related CAS

71214-29-4 (S-isomer)