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TFA-6-amino-hexanol-DMT-2-methyl linker

Catalog number: BRP-00728

TFA-6-amino-hexanol-DMT-2-methyl linker

TFA-6-amino-hexanol-DMT-2-methyl linker is a specialized phosphoramidite compound used in oligonucleotide synthesis. It consists of a phosphoramidite moiety, which serves as a linker to attach nucleotide units during synthesis. Additionally, it contains a 2-methyl group and a 6-amino-hexanol-DMT protective group, along with a trifluoroacetyl (TFA) moiety. These modifications ensure stability during synthesis and enable precise control over the addition of nucleotide units, facilitating the creation of custom oligonucleotides for various molecular biology and biotechnology applications.

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Catalog
BRP-00728
Synonyms
TFA-6-amino-hexanol-DMT-2-methyl Phosphoramidite; TFA-6-amino-hexanol-DMT-2-methyl (2-cyanoethyl)-(N,N-diisopropyl)-Phosphoramidite; TFA-6-amino-hexanol-DMT-2-methyl
IUPAC Name
2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-6-(2,2,2-trifluoroacetamido)hexyl (2-cyanoethyl) diisopropylphosphoramidite
Molecular Weight
745.82
Molecular Formula
C39H51F3N3O6P
SMILES
CC(N(C(C)C)P(OCCC#N)OCC(CCCCNC(C(F)(F)F)=O)COC(C1=CC=C(OC)C=C1)(C2=CC=C(OC)C=C2)C3=CC=CC=C3)C
InChI
InChI=1S/C39H51F3N3O6P/c1-29(2)45(30(3)4)52(50-26-12-24-43)51-28-31(13-10-11-25-44-37(46)39(40,41)42)27-49-38(32-14-8-7-9-15-32,33-16-20-35(47-5)21-17-33)34-18-22-36(48-6)23-19-34/h7-9,14-23,29-31H,10-13,25-28H2,1-6H3,(H,44,46)
InChIKey
HRDZFZSXSXGZQJ-UHFFFAOYSA-N
Purity
≥97%
Appearance
Colorless oily liquid
Storage
Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00728


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