Name: Stearyl Phosphoramidite
Brand: BOC Sciences
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Stearyl Phosphoramidite

Stearyl Phosphoramidite is a specialized reagent used in oligonucleotide synthesis to introduce a stearyl group (octadecyl chain) at the 5'-end of the oligonucleotide sequence. Stearyl groups are long-chain fatty acids that enhance the hydrophobicity and lipophilicity of the oligonucleotide, improving its ability to interact with lipid membranes. This modification is beneficial for developing oligonucleotide-based therapeutics and delivery systems, as it can enhance cellular uptake and stability. Stearyl-modified oligonucleotides are often used in gene silencing, antisense therapies, and other applications requiring efficient delivery and cellular internalization.

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Catalog

BRP-00547

Synonyms

1-Octadecanol CEP; C18-linker amidite; Octadecyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl octadecyl ester; 5'-Stearyl phosphoramidite

CAS

207273-84-5

IUPAC Name

3-[[di(propan-2-yl)amino]-octadecoxyphosphanyl]oxypropanenitrile

Molecular Weight

470.71

Molecular Formula

C27H55N2O2P

SMILES

CCCCCCCCCCCCCCCCCCOP(N(C(C)C)C(C)C)OCCC#N

InChI

InChI=1S/C27H55N2O2P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-24-30-32(31-25-22-23-28)29(26(2)3)27(4)5/h26-27H,6-22,24-25H2,1-5H3