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rG (Pac) CNA CPG is a modification reagent utilized in oligonucleotide synthesis. It incorporates a riboguanosine (rG) residue modified with a phenoxyacetyl (Pac) group onto a controlled pore glass (CPG) solid support. The ''CNA'' designation indicates the presence of a 2'-O-methylribonucleotide modification, enhancing nuclease resistance and stability. This reagent enables the synthesis of RNA oligonucleotides with specific chemical properties, such as increased resistance to nuclease degradation. These modified RNA oligonucleotides find applications in various research areas, including RNA interference (RNAi), gene expression regulation, and RNA-based therapeutics.
Chemical Structure:
-cna-cpg.gif)
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