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rG (iBu) CNA CPG is a modification reagent used in oligonucleotide synthesis for molecular biology and biotechnology applications. It introduces a riboguanosine (rG) residue modified with an isobutyryl (iBu) group onto a controlled pore glass (CPG) solid support. The "CNA" designation indicates the presence of a 2'-O-methylribonucleotide modification, enhancing nuclease resistance and stability. This modification enables the synthesis of RNA oligonucleotides with increased resistance to degradation, suitable for various research areas such as RNA interference and gene regulation studies. Additionally, the CPG support facilitates efficient solid-phase synthesis of oligonucleotides.
Chemical Structure:
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