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Revusiran - CAS 1438322-82-7

Catalog number: BRP-02076

Revusiran

Revusiran is a 1st-generation short interfering RNA, which directed against transthyretin (TTR) mRNA. Revusiran can be used for transthyretin (TTR)-mediated amyloidosis research.

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Catalog
BRP-02076
Synonyms
ALN-TTRSC; AD-51547; RNA, ((2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)G-Gm-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)U-Am-Am-Cm-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)A), 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate], complex with RNA (Um-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)C-Am-Um-Gm-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)C-Cm-(2'-deoxy-2'-fluoro)C-Am-sp-(2'-deoxy-2'-fluoro)U-sp-Cm) (1:1)
CAS
1438322-82-7
Sequence
RNA, (ucuugguuacaugaaaucccauc), complex with RNA (ugggauuucauguaaccaaga) (1:1)

Chemical Structure:


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BOC Sciences is a leading provider of DNA and RNA products and services that meet the needs of researchers and pharmaceutical companies worldwide. Its broad product portfolio includes various types of oligonucleotides, DNA/RNA synthesis feedstocks, RNA interference tools, and advanced drug delivery systems, among others. Designed to promote cutting-edge research and innovative therapeutic solutions, at BOC Sciences you are sure to find the right product for you.

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