Name: Reverse Abasic Phosphoramidite
Brand: BOC Sciences
Rating: 5 (1 reviews)

Reverse Abasic Phosphoramidite

Reverse Abasic Phosphoramidite is a specialized compound used in oligonucleotide synthesis. It allows for the controlled introduction of abasic sites, which are sites lacking a nucleobase, into oligonucleotide sequences. These abasic sites serve as versatile molecular tools for various applications in molecular biology, including studying nucleic acid structure, elucidating enzyme kinetics, and investigating nucleic acid-protein interactions.

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Catalog

BRP-00740

Synonyms

D-erythro-Pentitol, 1,4-anhydro-3-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-, 2-cyanoethyl bis(1-methylethyl)phosphoramidite; 3'-O-(4,4'-dimethoxytrityl)-1',2'-Dideoxy D-ribose-5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; ((2R,3S)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite

CAS

401813-16-9

IUPAC Name

3-[[(2R,3S)-3-[bis(4-methoxyphenyl)-phenylmethoxy]oxolan-2-yl]methoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

Molecular Weight

620.73

Molecular Formula

C35H45N2O6P

SMILES

CC(C)N(C(C)C)P(OCCC#N)OCC1C(CCO1)OC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC

InChI

InChI=1S/C35H45N2O6P/c1-26(2)37(27(3)4)44(41-23-10-22-36)42-25-34-33(21-24-40-34)43-35(28-11-8-7-9-12-28,29-13-17-31(38-5)18-14-29)30-15-19-32(39-6)20-16-30/h7-9,11-20,26-27,33-34H,10,21,23-25H2,1-6H3/t33-,34+,44?/m0/s1

InChIKey

WPNQXLQBMSUHFX-JUWSMZLESA-N

Purity

>98%

Appearance

White to faint yellow powder

Storage

Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00740