rC (Ac), 2'-OAc CNA CPG is a modification reagent employed in oligonucleotide synthesis. It introduces a ribocytidine (rC) residue modified with an acetyl (Ac) group onto a controlled pore glass (CPG) solid support. Additionally, it incorporates a 2'-O-acetyl modification to the ribose sugar and includes a 2'-O-methylribonucleotide (CNA) modification for heightened stability. This reagent facilitates the production of RNA oligonucleotides with specific chemical properties, such as increased resistance to nuclease degradation. These tailored RNA oligonucleotides are essential tools in diverse research areas, including RNA interference (RNAi), gene expression modulation, and RNA-based therapeutics.
Chemical Structure:
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