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Pseudouridine 5'-triphosphate tetrasodium salt - CAS 28022-82-4

Catalog number: BRP-00465

Pseudouridine 5'-triphosphate tetrasodium salt

Pseudouridine 5'-triphosphate tetrasodium salt is a modified nucleotide used in molecular biology. In its tetrasodium salt form, it's soluble in water. This compound is commonly used as a substrate in enzymatic reactions like transcription and reverse transcription. Its incorporation into RNA can introduce pseudouridine modifications, influencing RNA structure and function. These modifications play roles in mRNA splicing, translation efficiency, and RNA-protein interactions. In research, it helps study RNA modification dynamics and their impact on gene expression and disease mechanisms.

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Catalog
BRP-00465
Synonyms
Uracil, 5-β-D-ribofuranosyl-, 5'-(tetrahydrogen triphosphate), tetrasodium salt; Sodium ((2R,3S,4R,5S)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate; Pseudo-UTP sodium salt; Pseudo-UTP tetrasodium salt; 5-Ribosyl Uracil tetrasodium salt; 5'-triphospho-pseudouridine tetrasodium salt
CAS
28022-82-4
IUPAC Name
tetrasodium;[[[(2R,3S,4R,5S)-5-(2,4-dioxo-1H-pyrimidin-5-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate
Molecular Weight
572.07
Molecular Formula
C9H11N2Na4O15P3
Canonical SMILES
C1=C(C(=O)NC(=O)N1)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])O)O.[Na+].[Na+].[Na+].[Na+]
InChI
InChI=1S/C9H15N2O15P3.4Na/c12-5-4(2-23-28(19,20)26-29(21,22)25-27(16,17)18)24-7(6(5)13)3-1-10-9(15)11-8(3)14;;;;/h1,4-7,12-13H,2H2,(H,19,20)(H,21,22)(H2,16,17,18)(H2,10,11,14,15);;;;/q;4*+1/p-4/t4-,5-,6-,7+;;;;/m1..../s1
InChIKey
VLONFINCAQXDIZ-YQBQUZGCSA-J
Purity
≥97% by HPLC
Storage
Store at -20 °C
Related CAS
1175-34-4 (free acid)

Chemical Structure:


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