Name: Plozasiran
Brand: BOC Sciences
Rating: 5 (1 reviews)

Plozasiran

Plozasiran is an siRNA developed for the treatment of severe hypertriglyceridemia, mixed dyslipidemia and familial Chylomicronemia. It acts by targeting apolipoprotein C III.

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Catalog

BRP-02767

Synonyms

ARO-APOC3; RNA, ([1'-de(6-amino-9H-purin-9-yl)]dA-(5'→5')-sp-Am-Cm-Gm-Gm-Gm-Am-Cm-Am-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)A-Um-Um-Cm-Um-CmAm-Gm-Um-Im-Am-(3' →3')-sp-[1'-de(6-amino-9H-purin-9-yl)]dA), 3'-[O-[cis-4-[(3S,8S)-17-[[2-(acetylamino)-2-deoxy-βD-galactopyranosyl]oxy]-3,8-bis[[[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]carbonyl]-1,6,11-trioxo-15-oxa-2,7,12-triazaheptadec-1-yl]cyclohexyl]hydrogen phosphorothioate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)C-sp-Am-sp-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)G-Am-Gm-Am-Am-Um-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)CCm-(2'-deoxy-2'-fluoro)G-sp-Um) (1:1)

CAS

2379776-40-4

Molecular Weight

15618.77

Molecular Formula

C493H654F11N164O311P43S7

Solubility

Soluble in DMSO.

Appearance

White to off-white solid

Storage

Store at -20 °C

Related CAS

2379776-41-5 (sodium salt)

Chemical Structure:

Our Products

BOC Sciences is a leading provider of DNA and RNA products and services that meet the needs of researchers and pharmaceutical companies worldwide. Its broad product portfolio includes various types of oligonucleotides, DNA/RNA synthesis feedstocks, RNA interference tools, and advanced drug delivery systems, among others. Designed to promote cutting-edge research and innovative therapeutic solutions, at BOC Sciences you are sure to find the right product for you.

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