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Palmitate Phosphoramidite - CAS 1772522-18-5

Catalog number: BRP-00546

Palmitate Phosphoramidite

Palmitate Phosphoramidite is a specialized reagent used in oligonucleotide synthesis to introduce palmitic acid moieties into the oligonucleotide sequence. Palmitic acid is a saturated fatty acid commonly found in biological membranes and is known for its amphipathic properties. By attaching palmitic acid to oligonucleotides, researchers can modify the properties of the resulting conjugates, such as enhancing membrane permeability or promoting lipid bilayer interactions. This modification enables the development of oligonucleotide-based therapeutics, drug delivery systems, and molecular probes with improved cellular uptake and stability.

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Catalog
BRP-00546
Synonyms
Palmityl-6-aminohexyl [(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 6-[(1-oxohexadecyl)amino]hexyl ester; 2-Cyanoethyl 6-[(1-oxohexadecyl)amino]hexyl N,N-bis(1-methylethyl)phosphoramidite; Palmitic Aminohexanol Amidite; 2-cyanoethyl (6-palmitamidohexyl) diisopropylphosphoramidite; Palmitic Aminohexanol Phosphoramidite
CAS
1772522-18-5
IUPAC Name
N-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]hexadecanamide
Molecular Weight
555.82
Molecular Formula
C31H62N3O3P
SMILES
CCCCCCCCCCCCCCCC(=O)NCCCCCCOP(N(C(C)C)C(C)C)OCCC#N
InChI
InChI=1S/C31H62N3O3P/c1-6-7-8-9-10-11-12-13-14-15-16-17-20-24-31(35)33-26-21-18-19-22-27-36-38(37-28-23-25-32)34(29(2)3)30(4)5/h29-30H,6-24,26-28H2,1-5H3,(H,33,35)
InChIKey
BFUDAHSNZSPONN-UHFFFAOYSA-N
Purity
≥90% by HPLC
Appearance
White to off-white solid
Storage
Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00546


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