Nedosiran - CAS 2266591-83-5

BRP-02087

DCR-PHXC; DCR PHXC; RNA, (Am-sp-Um-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)U-Gm-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)C-Um-Gm-Am-Gm-Cm-Am-Gm-Cm-Cm-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]G-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-Gm-Gm-Cm-Um-Gm-Cm), complex with RNA ([1-de-β-D-ribofuranosyl-1-[(2R,3R,4S,5R)-tetrahydro-4-hydroxy-5-[(hydroxymethoxyphosphinyl)methoxy]-3-methoxy-2-furanyl]]U-(4'→5')-sp-(2'-deoxy-2'-fluoro)C-sp-(2'-deoxy-2'-fluoro)A-sp-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-Am-Gm-Gm-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)C-Am-Um-sp-Gm-sp-Gm) (1:1)

2266591-83-5

20,985 Da

C662H865F19N231O413P57S6

Store at -20 °C

RNA, (auguuguccuuuuuaucugagcagccgaaaggcugc), complex with RNA (ucagauaaaaaggacaacaugg) (1:1)

2247026-22-6 (sodium salt)