DMT-dP-CE-Phosphoramidite - CAS 2133842-85-8

Catalog number: BRP-02202

DMT-dP-CE-Phosphoramidite

DMT-dP-CE-Phosphoramidite is crucial for the automated synthesis of oligonucleotides, providing the necessary protection for functional groups to ensure accurate and efficient sequence assembly. The modified base ''dP'' allows for the incorporation of unique features into the oligonucleotides, which can be tailored for specific research, diagnostic, or therapeutic applications.

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Catalog
BRP-02202
Synonyms
Nap-dU Phosphoramidite; DMTr-5-[N-(naphthalen-2-ylmethyl)formamide]-dU-3'-CE-Phosphoramidite; Nap-dU CEP; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[5-(naphthalen-1-ylmethyl)carbamoyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS
2133842-85-8
IUPAC Name
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-((naphthalen-1-ylmethyl)carbamoyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
Molecular Weight
913.99
Molecular Formula
C51H56N5O9P
Canonical SMILES
N#CCCOP(OC1CC(OC1COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C=C(C(=O)NC5=O)C(=O)NCC6=CC=CC=7C=CC=CC76)N(C(C)C)C(C)C
InChI
InChI=1S/C51H56N5O9P/c1-34(2)56(35(3)4)66(63-29-13-28-52)65-45-30-47(55-32-44(49(58)54-50(55)59)48(57)53-31-37-16-12-15-36-14-10-11-19-43(36)37)64-46(45)33-62-51(38-17-8-7-9-18-38,39-20-24-41(60-5)25-21-39)40-22-26-42(61-6)27-23-40/h7-12,14-27,32,34-35,45-47H,13,29-31,33H2,1-6H3,(H,53,57)(H,54,58,59)/t45-,46+,47+,66?/m0/s1
InChIKey
WAQZWDAZYFQSHE-CNYVYYQHSA-N
Purity
≥95%
Storage
Store at -20 °C

Chemical Structure:

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