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N4-Bz-5'-O-DMTr-2'-O-Me-cytidine-3'-CED-phosphoramidite - CAS 110764-78-8

Catalog number: BRP-02177

N4-Bz-5'-O-DMTr-2'-O-Me-cytidine-3'-CED-phosphoramidite

N4-Bz-5'-O-DMTr-2'-O-Me-cytidine-3'-CED-phosphoramidite is a modified phosphoramidite designed for use in the synthesis of stable and efficient oligonucleotides. Its protective groups and modifications enhance the stability of the resulting nucleic acids and facilitate their incorporation into nucleic acid chains during solid-phase synthesis. This compound is crucial in the production of antisense oligonucleotides, siRNA, probes, and primers, providing enhanced resistance to enzymatic degradation and improved performance in various applications.

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Catalog
BRP-02177
Synonyms
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methycytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 2'-O-Me-C(Bz)-3'-phosphoramidite; 2'-OMe-Bz-C Phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylcytidine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-methylcytidine; N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
CAS
110764-78-8
IUPAC Name
N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
Molecular Weight
863.93
Molecular Formula
C47H54N5O9P
Canonical SMILES
CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OC)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC
InChI
InChI=1S/C47H54N5O9P/c1-32(2)52(33(3)4)62(59-30-14-28-48)61-42-40(60-45(43(42)57-7)51-29-27-41(50-46(51)54)49-44(53)34-15-10-8-11-16-34)31-58-47(35-17-12-9-13-18-35,36-19-23-38(55-5)24-20-36)37-21-25-39(56-6)26-22-37/h8-13,15-27,29,32-33,40,42-43,45H,14,30-31H2,1-7H3,(H,49,50,53,54)/t40-,42-,43-,45-,62?/m1/s1
InChIKey
JFFSFQRVIPPCBC-VKBHKTMGSA-N
Purity
≥95%
Appearance
White Powder
Storage
Store at -20 °C

Chemical Structure:


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BOC Sciences is a leading provider of DNA and RNA products and services that meet the needs of researchers and pharmaceutical companies worldwide. Its broad product portfolio includes various types of oligonucleotides, DNA/RNA synthesis feedstocks, RNA interference tools, and advanced drug delivery systems, among others. Designed to promote cutting-edge research and innovative therapeutic solutions, at BOC Sciences you are sure to find the right product for you.

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