Name: 5'-O-DMT-N4-Benzoyl-3'-O-tert-butyldimethylsilyl-cytidine 2'-CE phosphoramidite
Brand: BOC Sciences
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5'-O-DMT-N4-Benzoyl-3'-O-tert-butyldimethylsilyl-cytidine 2'-CE phosphoramidite

5'-O-DMT-N4-Benzoyl-3'-O-tert-butyldimethylsilyl-cytidine 2'-CE phosphoramidite, a highly acclaimed reagent in the realm of biomedicine, exhibits unparalleled significance. Notably, this phosphoramidite derivative finds widespread employment in the synthesis of altered oligonucleotides, exuding immense promise for gene therapy, drug conveyance, and diagnostic modalities.

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Catalog

BRP-02193

Synonyms

N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 2'-CE phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 3'-TBDMS-Bz-rC Phosphoramidite; 3'-O-TBDMS-5'-O-DMT-N4-Bz-rC CED phosphoramidite; 5'-O-DMT-3'-TBDMS-N4-benzoyl-cytidine 2'-CE phosphoramidite

CAS

129470-47-9

IUPAC Name

N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

Molecular Weight

964.17

Molecular Formula

C52H66N5O9PSi

Canonical SMILES

CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O[Si](C)(C)C(C)(C)C

InChI

InChI=1S/C52H66N5O9PSi/c1-36(2)57(37(3)4)67(63-34-18-32-53)65-47-46(66-68(10,11)51(5,6)7)44(64-49(47)56-33-31-45(55-50(56)59)54-48(58)38-19-14-12-15-20-38)35-62-52(39-21-16-13-17-22-39,40-23-27-42(60-8)28-24-40)41-25-29-43(61-9)30-26-41/h12-17,19-31,33,36-37,44,46-47,49H,18,34-35H2,1-11H3,(H,54,55,58,59)/t44-,46-,47-,49-,67?/m1/s1

InChIKey

KGHSXHZESVOJIE-YOVDOAOFSA-N

Purity

≥97% by HPLC

Chemical Structure:

Our Products

BOC Sciences is a leading provider of DNA and RNA products and services that meet the needs of researchers and pharmaceutical companies worldwide. Its broad product portfolio includes various types of oligonucleotides, DNA/RNA synthesis feedstocks, RNA interference tools, and advanced drug delivery systems, among others. Designed to promote cutting-edge research and innovative therapeutic solutions, at BOC Sciences you are sure to find the right product for you.

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