CAS 121058-88-6 Ac-rC Phosphoramidite

Ac-rC Phosphoramidite

Ac-rC Phosphoramidite is a commonly used protected 2-OTBDMS phosphoramidite for incorporating cytidine nucleotides into synthetic oligonucleotides.

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Ordering Information

Catalog Number	Size	Price	Stock	Quantity
BRP-02156	25 g	$598	In stock

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Catalog

BRP-02156

Synonyms

N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 5'-O-DMT-2'-O-tert-butyldimethylsilyl-N4-Acetyl-cytidine 3'-CE phosphoramiditee; 5'-O-(4,4'-DiMethoxytrityl)-N4-acetyl-2'-O-t-butyldimethylsilylcytidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 5'-O-DMTr-N4-Ac-2'-O-TBDMS-cytidine-3'-CED PhosphoraMidite; DMT-2'-O-TBDMS-rC(ac) Phosphoramidite; 2'-TBDMS-Ac-rC-CE-Phosphoramidite; 5'-DMT-2'-O-TBDMS-N4-Acetyl-Cytidine Phosphoramidite

CAS

121058-88-6

IUPAC Name

N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

Molecular Weight

902.11

Molecular Formula

C47H64N5O9PSi

Canonical SMILES

CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

InChI

InChI=1S/C47H64N5O9PSi/c1-32(2)52(33(3)4)62(58-30-16-28-48)60-42-40(59-44(43(42)61-63(11,12)46(6,7)8)51-29-27-41(49-34(5)53)50-45(51)54)31-57-47(35-17-14-13-15-18-35,36-19-23-38(55-9)24-20-36)37-21-25-39(56-10)26-22-37/h13-15,17-27,29,32-33,40,42-44H,16,30-31H2,1-12H3,(H,49,50,53,54)/t40-,42-,43-,44-,62?/m1/s1

InChIKey

QKWKXYVKGFKODW-YOEDQOPESA-N

Purity

≥98% by HPLC

Appearance

White to Off-white Powder

Storage

Store at 2-8 °C

Related CAS

237060-94-5 (S-isomer)

Chemical Structure:

Ac-rC Phosphoramidite - CAS 121058-88-6

Ac-rC Phosphoramidite