Name: Morpholino G(PhAc) subunit
Brand: BOC Sciences
Rating: 5 (1 reviews)

Morpholino G(PhAc) subunit

The Morpholino G(PhAc) subunit is a component used in the synthesis of morpholino oligomers, synthetic analogs of nucleic acids. It features a morpholine ring structure as the backbone, with a guanine base modified by a phenylacetyl group (PhAc). This modification enhances the binding affinity of the oligomers to complementary RNA or DNA targets. The Morpholino G(PhAc) subunit is utilized in molecular biology and biotechnology for applications such as gene knockdown experiments, antisense therapy, and the study of gene function.

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Catalog

BRP-00433

Synonyms

Phosphoramidochloridic acid, N,N-dimethyl-, [(2S,6R)-6-[1,6-dihydro-6-oxo-2-[(2-phenylacetyl)amino]-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester; [(2S,6R)-6-[1,6-Dihydro-6-oxo-2-[(2-phenylacetyl)amino]-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl N,N-dimethylphosphoramidochloridate; (2S,6R)-6-(6-oxo-2-(2-phenylacetamido)-1H-purin-9(6H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate

CAS

1044241-74-8

IUPAC Name

((2S,6R)-6-(6-oxo-2-(2-phenylacetamido)-1,6-dihydro-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate

Molecular Weight

752.20

Molecular Formula

C39H39ClN7O5P

SMILES

O=C1N=C(NC(=O)CC=2C=CC=CC2)NC3=C1N=CN3C4OC(COP(=O)(Cl)N(C)C)CN(C4)C(C=5C=CC=CC5)(C=6C=CC=CC6)C=7C=CC=CC7

InChI

InChI=1S/C39H39ClN7O5P/c1-45(2)53(40,50)51-26-32-24-46(39(29-17-9-4-10-18-29,30-19-11-5-12-20-30)31-21-13-6-14-22-31)25-34(52-32)47-27-41-35-36(47)43-38(44-37(35)49)42-33(48)23-28-15-7-3-8-16-28/h3-22,27,32,34H,23-26H2,1-2H3,(H2,42,43,44,48,49)/t32-,34+,53?/m0/s1

InChIKey

NURVOJDGJURYKG-BFXPVMCSSA-N

Purity

≥98% by HPLC

Density

1.37±0.1 g/cm3

Appearance

White to off-white powder

Storage

Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00433