Name: m7GpppAmpG
Brand: BOC Sciences
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m7GpppAmpG

m7GpppAmpG is a trinucleotide 5' cap analog with the capping efficiencies for the obtained RNAs of 90%. It is used to transcribe 5'cap mRNA in vitro to produce the Cap 1 structure, which is more suitable for mammalian systems and has higher transcriptional efficiency than the Cap 0 structure. m7GpppAmpG Cap Analog is a co-transcriptional capping agent that transcribes 5' capped mRNA in vitro to form the Cap 1 structure.

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Catalog

BRP-00215

Synonyms

m7G(5')ppp(5')(2'-OMeA)pG; GAG; Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt; Adenosine 5'-(tetrahydrogen triphosphate), guanylyl-(5'→3')-2'-O-methyl-, P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt; m7GpppA2'OmepG

CAS

62858-30-4

IUPAC Name

[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[(2R,3R,4R,5R)-3-[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] phosphate

Molecular Weight

1145.67

Molecular Formula

C32H43N15O24P4

SMILES

CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)OC)OP(=O)(O)OCC7C(C(C(O7)N8C=NC9=C8N=C(NC9=O)N)O)O)O)O

InChI

InChI=1S/C32H43N15O24P4/c1-44-9-47(25-15(44)27(53)43-32(35)41-25)29-19(51)17(49)11(67-29)4-64-73(56,57)70-75(60,61)71-74(58,59)65-5-12-20(21(62-2)30(68-12)45-7-38-13-22(33)36-6-37-23(13)45)69-72(54,55)63-3-10-16(48)18(50)28(66-10)46-8-39-14-24(46)40-31(34)42-26(14)52/h6-12,16-21,28-30,48-51H,3-5H2,1-2H3,(H11-,33,34,35,36,37,40,41,42,43,52,53,54,55,56,57,58,59,60,61)/t10-,11-,12-,16-,17-,18-,19-,20-,21-,28-,29-,30-/m1/s1

InChIKey

AGWRKMKSPDCRHI-UQTMIEBXSA-N

Purity

≥95% by HPLC

Storage

Store at -20 °C

Related CAS

2941382-07-4 (trisodium salt) 2710263-09-3 (triammonium salt)

Chemical Structure:

Chemical structure of BRP-00215