LZCapAU(3'Acm)

LZCapAU(3'Acm), a Cap1 analogue, can be used as an mRNA co-transcription capping reagent. Under the action of T7 polymerase, LZCapAU(3'Acm), NTPs and template DNA are co-transcribed to produce mRNA with 5 'end Cap1 structure. Capped mRNA can be directly translated and expressed in cells and in vivo. It is widely used in in vitro transcription, gene editing, vaccine development, tumor CAR-T therapy, protein replacement therapy and regenerative medicine.

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Catalog

BRP-00435

Synonyms

m7(3'Acm)Gppp(2'OMe)ApU; LZCapAU(3'Acm) ammonium salt; (2R,3R,4R,5R)-2-((((((((((2S,3S,4R,5R)-3-(acetamidomethyl)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl) phosphate ammonium salt

Molecular Weight

1161.71 (free acid)

Molecular Formula

C34H47N13O25P4 (free acid)

Purity

≥95% by HPLC

Storage

Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00435