LZCapAG(3'Ma-Biotin)

LZCapAG(3'Ma-Biotin), a Cap1 analog with a Biotin label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-Biotin), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. LZCapAG(3'Ma-Biotin) capped mRNA, with a Biotin label, can bind to streptomycin magnetic beads to explore a variety of biological functions.

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Catalog

BRP-00436

Synonyms

m7(3'Ma-Biotin)Gppp(2'OMe)ApG; LZCapAG(3'Ma-Biotin) ammonium salt; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3R,4R,5R)-2-((((((((((2S,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxy-3-((5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)methyl)tetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl) phosphate ammonium salt

Molecular Weight

1385.01 (free acid)

Molecular Formula

C43H60N18O25P4S (free acid)

Purity

≥90% by HPLC

Storage

Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00436