LZCapAG(3'Acm) GLuc mRNA

LZCapAG(3'Acm) GLuc mRNA

Gaussia Luciferase (GLuc) is the smallest (20 kD) naturally secreted luciferase known in vivo. When using Gaussia Luciferase to perform fluorescence report experiment, the cell supernatant can be directly used for detection. The luciferase catalyzes the oxidation of the substrate coelenterin and emits light (480 nm) without the involvement of ATP. LZCapAG(3'Acm) GLuc mRNA was synthesized and purified from linear template one-step transcription by T7 transcriptase and LZCapAG(3'Acm) cap analogs. Compared with the Cap0 structure and other commercially available Cap1 structures, the Cap1 structure of LZCapAG(3'Acm) enables more efficient and durable mRNA expression. LZCapAG(3'Acm) GLuc mRNA has poly A and optimized 5 'UTR and 3' UTR structure, which can improve mRNA stability and promote mRNA translation to achieve a better expression effect. LZCapAG(3'Acm) GLuc mRNA is suitable for mRNA delivery, translation efficiency and transfection efficiency experiments.

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