LZCapAG(3'Acm)

LZCapAG(3'Acm), a Cap1 analogue, can be used as an mRNA co-transcription capping reagent. Under the action of T7 polymerase, LZCapAG(3'Acm), NTPs and template DNA are co-transcribed to produce mRNA with 5 'end Cap1 structure. Capped mRNA can be directly translated and expressed in cells and in vivo. It is widely used in in vitro transcription, gene editing, vaccine development, tumor CAR-T therapy, protein replacement therapy and regenerative medicine.

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Catalog

BRP-00434

Synonyms

m7(3'Acm)Gppp(2'OMe)ApG; 9-((2R,3R,4S,5S)-4-(acetamidomethyl)-5-((((((((((2R,3R,4R,5R)-3-(((((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3-hydroxytetrahydrofuran-2-yl)-2-amino-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium ammonium salt; LZCapAG(3'Acm) ammonium salt

Molecular Weight

1200.75 (free acid)

Molecular Formula

C35H48N16O24P4 (free acid)

Purity

≥95% by HPLC

Storage

Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00434