Name: LNA-UTP
Brand: BOC Sciences
Rating: 5 (1 reviews)

LNA-UTP

LNA-UTP, or Locked Nucleic Acid-uridine triphosphate, is a modified nucleotide used in biochemical and molecular biology research. It contains a uridine base modified with a locked nucleic acid (LNA) backbone and linked to a triphosphate group. This modified nucleotide is employed in studies related to RNA and DNA research, where LNA modifications enhance the stability and specificity of oligonucleotides. LNA-UTP can be incorporated into RNA strands during synthesis, allowing researchers to investigate various aspects of nucleic acid structure, function, and interactions.

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Catalog

BRP-00929

Synonyms

2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-; 1-[2,5-Anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-2,4(1H,3H)-pyrimidinedione; LNA-U-TP; ((1R,3R,4R,7S)-3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl tetrahydrogen triphosphate

CAS

1258616-54-4

IUPAC Name

[[(1R,3R,4R,7S)-3-(2,4-dioxopyrimidin-1-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

Molecular Weight

496.15

Molecular Formula

C10H15N2O15P3

SMILES

C1C2(C(C(O1)C(O2)N3C=CC(=O)NC3=O)O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O

InChI

InChI=1S/C10H15N2O15P3/c13-5-1-2-12(9(15)11-5)8-6-7(14)10(25-8,3-23-6)4-24-29(19,20)27-30(21,22)26-28(16,17)18/h1-2,6-8,14H,3-4H2,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18)/t6-,7+,8-,10-/m1/s1

InChIKey

RSSDTUFQOLIPRO-IBCQBUCCSA-N

Purity

95%

Density

2.109±0.06 g/cm3

Solubility

Soluble in Water

Appearance

Lyophilized white powder

Storage

Store at -20 °C