LNA-GTP sodium salt

LNA-GTP sodium salt is a modified form of guanosine triphosphate (GTP) where an LNA modification is incorporated into the ribose sugar moiety. Similar to LNA-ATP, this modification enhances the stability and binding affinity of GTP to complementary RNA or DNA targets. The sodium salt form improves the solubility and stability of LNA-GTP, making it useful for applications such as RNAi, antisense oligonucleotide therapeutics, and RNA-based diagnostics.

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Catalog

BRP-00653

Synonyms

2-Amino-9-[2,5-anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-1,9-dihydro-6H-purin-6-one sodium salt

IUPAC Name

sodium;((1R,3R,4R,7S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl tetrahydrogen triphosphate

Molecular Weight

535.19 (free acid)

Molecular Formula

C11H16N5O14P3 (free acid)

Purity

≥98%

Storage

Store at -20 °C, Always avoid freeze-thaw cycles

Related CAS

2763213-03-0 (tetrasodium salt) 1233876-29-3 (free acid)