Name: LNA-CTP
Brand: BOC Sciences
Rating: 5 (1 reviews)

LNA-CTP

LNA-CTP, or Locked Nucleic Acid-cytidine triphosphate, is a modified nucleotide used in biochemical and molecular biology research. It contains a cytidine base modified with a locked nucleic acid (LNA) backbone and linked to a triphosphate group. This modified nucleotide is utilized in studies related to RNA and DNA research, where LNA modifications enhance the stability and specificity of oligonucleotides. LNA-CTP can be incorporated into RNA or DNA strands during synthesis, allowing researchers to investigate various aspects of nucleic acid structure, function, and interactions.

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Catalog

BRP-00928

Synonyms

2(1H)-Pyrimidinone, 4-amino-1-[2,5-anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-; 4-Amino-1-[2,5-anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-2(1H)-pyrimidinone; LNA-C-TP; ((1R,3R,4R,7S)-3-(4-amino-2-oxopyrimidin-1(2H)-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl tetrahydrogen triphosphate

CAS

847650-98-0

IUPAC Name

[[(1R,3R,4R,7S)-3-(4-amino-2-oxopyrimidin-1-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

Molecular Weight

495.17

Molecular Formula

C10H16N3O14P3

SMILES

C1C2(C(C(O1)C(O2)N3C=CC(=NC3=O)N)O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O

InChI

InChI=1S/C10H16N3O14P3/c11-5-1-2-13(9(15)12-5)8-6-7(14)10(25-8,3-23-6)4-24-29(19,20)27-30(21,22)26-28(16,17)18/h1-2,6-8,14H,3-4H2,(H,19,20)(H,21,22)(H2,11,12,15)(H2,16,17,18)/t6-,7+,8-,10-/m1/s1

InChIKey

LSTGCLQXGYREJT-IBCQBUCCSA-N

Boiling Point

837.7±75.0 °C at 760 mmHg

Purity

95%

Density

2.54±0.1 g/cm3

Solubility

Soluble in Water

Appearance

Lyophilized white powder