Name: Im(m7GDP)
Brand: BOC Sciences
Rating: 5 (1 reviews)

Im(m7GDP)

Im(m7GDP), or 7-methylguanosine diphosphate imidazole, is a modified nucleotide commonly used in biochemistry and molecular biology research. It features a 7-methylguanosine moiety, which mimics the 5' cap structure of eukaryotic mRNA, and is conjugated with diphosphate and imidazole groups. This compound is particularly useful for studying mRNA capping, translation initiation, and mRNA stability, as well as for synthesizing capped RNA molecules for various experimental applications, including in vitro transcription and RNA-protein interaction studies.

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Catalog

BRP-00379

Synonyms

5'-Guanylic acid, 7-methyl-, inner salt, anhydride with P-1H-imidazol-1-ylphosphonic acid (1:1); 5'-Guanylic acid, 7-methyl-, inner salt, monoanhydride with 1H-imidazol-1-ylphosphonic acid; m7Gpp; 7-methyl-guanosine diphosphate, IM; 7-methylguanosine diphosphate imidazole

CAS

531553-69-2

IUPAC Name

[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [hydroxy(imidazol-1-yl)phosphoryl] phosphate

Molecular Weight

507.29

Molecular Formula

C14H19N7O10P2

SMILES

CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)(N4C=CN=C4)O)O)O

InChI

InChI=1S/C14H19N7O10P2/c1-19-6-21(11-8(19)12(24)18-14(15)17-11)13-10(23)9(22)7(30-13)4-29-33(27,28)31-32(25,26)20-3-2-16-5-20/h2-3,5-7,9-10,13,22-23H,4H2,1H3,(H4-,15,17,18,24,25,26,27,28)/t7-,9-,10-,13-/m1/s1

InChIKey

FSLUCUBHOZVVQK-QYVSTXNMSA-N

Purity

≥95%

Appearance

White to off-white powder

Storage

Store at -20 °C, Keep in a dark and dry place

Chemical Structure:

Chemical structure of BRP-00379