Name: DMTr-2'-O-EOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite
Brand: BOC Sciences
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DMTr-2'-O-EOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite

DMTr-2'-O-EOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis and contains a 2'-O-ethoxyethyl (EOE) group at the 2'-position of 5-methylcytidine (5-Me-rC), along with benzoyl (Bz) protection on the cytosine amino group. Additionally, it features a cyanoethyl (CE) group at the 3'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified 5-methylcytidine residues into RNA sequences, enhancing stability and target specificity.

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Catalog

BRP-00617

IUPAC Name

(2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-ethoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

Molecular Weight

936.06

Molecular Formula

C51H62N5O10P

InChI

InChI=1S/C51H62N5O10P/c1-9-61-31-32-62-46-45(66-67(64-30-16-29-52)56(35(2)3)36(4)5)44(65-49(46)55-33-37(6)47(54-50(55)58)53-48(57)38-17-12-10-13-18-38)34-63-51(39-19-14-11-15-20-39,40-21-25-42(59-7)26-22-40)41-23-27-43(60-8)28-24-41/h10-15,17-28,33,35-36,44-46,49H,9,16,30-32,34H2,1-8H3,(H,53,54,57,58)/t44-,45-,46-,49-,67?/m1/s1

InChIKey

GFURHQMVDLZCAG-JMTVAXSASA-N

Purity

≥95%

Storage

Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00617