Name: 2,6-Diamino(N2,N6-diPac)-DMT-2'-O-TBDMS-purine riboside-CE-Phosphoramidite
Brand: BOC Sciences
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2,6-Diamino(N2,N6-diPac)-DMT-2'-O-TBDMS-purine riboside-CE-Phosphoramidite

2,6-Diamino(N2,N6-diPac)-DMT-2'-O-TBDMS-purine riboside-CE-phosphoramidite is a modified phosphoramidite reagent used for the synthesis of oligonucleotides. It features multiple protective groups: a dimethoxytrityl (DMT) group at the 5'-hydroxyl position, a tert-butyldimethylsilyl (TBDMS) group at the 2'-hydroxyl position, and cyanoethyl (CE) group on the phosphoramidite at the 3' position. These modifications ensure the stability and integrity of the purine riboside during the synthesis process, facilitating the creation of high-quality, stable oligonucleotides for research and therapeutic applications.

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Catalog

BRP-02200

Synonyms

(2R,3R,4R,5R)-5-(2,6-bis(2-phenoxyacetamido)-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; Diaminopurine (di-PAC) CED phosphoramidite; 2,6-Diamino(N2,N6-diPhenoxyacetyl)-5'-O-(4,4'-Dimethoxytrityl)-2'-O-tert-butyldimethylsilyl-purine riboside-3'-cyanoethyl Phosphoramidite; DMT-2'-O-TBDMS-N2-Pac-A(N6-Pac) 3'-CE-Phosphoramidite

CAS

2101776-87-6

IUPAC Name

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-[(2-phenoxyacetyl)amino]purin-6-yl]-2-phenoxyacetamide

Molecular Weight

1167.37

Molecular Formula

C62H75N8O11PSi

Canonical SMILES

CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=NC3=C(N=C(N=C32)NC(=O)COC4=CC=CC=C4)NC(=O)COC5=CC=CC=C5)COC(C6=CC=CC=C6)(C7=CC=C(C=C7)OC)C8=CC=C(C=C8)OC

InChI

InChI=1S/C62H75N8O11PSi/c1-42(2)70(43(3)4)82(78-37-21-36-63)80-55-51(38-77-62(44-22-15-12-16-23-44,45-28-32-47(73-8)33-29-45)46-30-34-48(74-9)35-31-46)79-59(56(55)81-83(10,11)61(5,6)7)69-41-64-54-57(65-52(71)39-75-49-24-17-13-18-25-49)67-60(68-58(54)69)66-53(72)40-76-50-26-19-14-20-27-50/h12-20,22-35,41-43,51,55-56,59H,21,37-40H2,1-11H3,(H2,65,66,67,68,71,72)/t51-,55-,56-,59-,82?/m1/s1

InChIKey

LFCZZILBKNBHDI-IGXISVFNSA-N

Chemical Structure:

Our Products

BOC Sciences is a leading provider of DNA and RNA products and services that meet the needs of researchers and pharmaceutical companies worldwide. Its broad product portfolio includes various types of oligonucleotides, DNA/RNA synthesis feedstocks, RNA interference tools, and advanced drug delivery systems, among others. Designed to promote cutting-edge research and innovative therapeutic solutions, at BOC Sciences you are sure to find the right product for you.

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