dG-CPG; 2000 Å

Catalog number: BRP-02257

dG-CPG; 2000 Å

dG-CPG; 2000 Å is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating N2-isobutyryl-deoxyguanosine (dG) residues. It includes a 5'-O-DMT (dimethoxytrityl) protective group, which protects the 5' end of the guanine base during synthesis. The N2-isobutyryl group protects the guanine's exocyclic amino group, and the 3'-suc (succinyl) linker connects the nucleoside to controlled pore glass (CPG) with a 2000 Å pore size. This configuration supports efficient synthesis and loading of long DNA sequences while ensuring precise incorporation and protection of guanine residues.

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Catalog
BRP-02257
Synonyms
dG-CPG 2000; 5'-Dimethoxytrityl-N-isobutyryl-2'-deoxyGuanosine, 3'-succinoyl-long chain alkylamino-CPG 2000; 5'-O-DMT-2'-deoxy-G(iBu)-3'-suc-CPG 2000
Appearance
White to Off-white Powder
Storage
Store at -20 °C

Chemical Structure:

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