Name: DDP-Amidite
Brand: BOC Sciences
Rating: 5 (1 reviews)

DDP-Amidite

DDP-Amidite is a specialized reagent used in oligonucleotide synthesis. It features a 1,3-di-O-(4,4'-dimethoxytrityl)-glycerol modification attached to a controlled efficiency (CE) phosphoramidite backbone. This modification provides a coupling site for the addition of nucleotide units during solid-phase synthesis, enabling the controlled construction of oligonucleotide sequences. Overall, this reagent facilitates the efficient and precise synthesis of oligonucleotides with specific chemical properties, suitable for various molecular biology and biotechnology applications.

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Catalog

BRP-00516

Synonyms

Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-[bis(4-methoxyphenyl)phenylmethoxy]-1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]ethyl 2-cyanoethyl ester; 2-[Bis(4-methoxyphenyl)phenylmethoxy]-1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]ethyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-[bis(4-methoxyphenyl)phenylmethoxy]-1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]ethyl 2-cyanoethyl ester; Symmetrical branching CED phosphoramidite; 1,3-di-O-DMTr-glycerol-CE-Phosphoramidite; 1,3-di-O-(4,4'-dimethoxytrityl)-glycerol-CE-Phosphoramidite

CAS

125922-95-4

IUPAC Name

3-[1,3-bis[bis(4-methoxyphenyl)-phenylmethoxy]propan-2-yloxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

Molecular Weight

897.04

Molecular Formula

C54H61N2O8P

SMILES

CC(C)N(C(C)C)P(OCCC#N)OC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

InChI

InChI=1S/C54H61N2O8P/c1-40(2)56(41(3)4)65(63-37-15-36-55)64-52(38-61-53(42-16-11-9-12-17-42,44-20-28-48(57-5)29-21-44)45-22-30-49(58-6)31-23-45)39-62-54(43-18-13-10-14-19-43,46-24-32-50(59-7)33-25-46)47-26-34-51(60-8)35-27-47/h9-14,16-35,40-41,52H,15,37-39H2,1-8H3

InChIKey

ATSHTKCDALIGCV-UHFFFAOYSA-N

Purity

≥95% by HPLC

Appearance

White, off-white to light yellow powder

Storage

Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00516