Cosdosiran

Cosdosiran is an siRNA targeting caspase-2, an enzyme involved in apoptosis. It was developed for the treatment of eye diseases—nonarteritic anterior ischaemic optic neuropathy (NAION) and primary angle closure glaucoma.

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Catalog

BRP-02771

Synonyms

QPI-1007; RNA, (A-Gm-G-Am-G-Um-U-Cm-C-A-Cm-A-Um-U-Cm-U-Gm-G-Cm), complex with RNA ([1'-de(6-amino-9H-purin-9-yl)]dA-(5'→5')-G-C-C-A-G-A-A-U-G-U-G-G-A-A-C-U-C-β-L-dC-U) (1:1)

CAS

1834560-88-1

Solubility

Soluble in DMSO.

Appearance

White to off-white solid

Storage

Store at -20 °C

Chemical Structure: