Bz-5-Me-C-LNA-CPG is a specialized reagent used in the synthesis of oligonucleotides. It features a benzoyl (Bz) protecting group on 5-methylcytosine (5-Me-C) and incorporates Locked Nucleic Acid (LNA) for enhanced binding affinity and stability. The reagent is immobilized on Controlled Pore Glass (CPG), facilitating efficient solid-phase synthesis. This combination of modifications results in high-affinity, stable oligonucleotides suitable for applications in molecular diagnostics, therapeutic development, and advanced research.
Chemical Structure:
