Name: Acridine Phosphoramidite
Brand: BOC Sciences
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Acridine Phosphoramidite

Acridine Phosphoramidite is a specialized reagent used in oligonucleotide synthesis to introduce acridine moieties into the oligonucleotide sequence. Acridine derivatives are known for their unique fluorescence properties, making them valuable for applications such as nucleic acid labeling, detection, and imaging. By incorporating acridine moieties into oligonucleotides, researchers can develop probes and molecular tools for studying DNA/RNA structure, dynamics, and interactions. This modification enables sensitive detection and visualization of nucleic acids in various biological assays and techniques, including fluorescence microscopy, in situ hybridization, and nucleic acid-based sensors.

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Catalog

BRP-00543

Synonyms

1-Dimethoxytrityloxy-2-(N-acridinyl-4-aminobutyl)-propyl-3-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-6-[(6-chloro-2-methoxy-9-acridinyl)amino]hexyl 2-cyanoethyl ester; 2-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-6-[(6-chloro-2-methoxy-9-acridinyl)amino]hexyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-6-[(6-chloro-2-methoxy-9-acridinyl)amino]hexyl 2-cyanoethyl ester

CAS

402829-33-8

IUPAC Name

3-[[2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-6-[(6-chloro-2-methoxyacridin-9-yl)amino]hexoxy]-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

Molecular Weight

891.47

Molecular Formula

C51H60ClN4O6P

SMILES

CC(C)N(C(C)C)P(OCCC#N)OCC(CCCCNC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

InChI

InChI=1S/C51H60ClN4O6P/c1-36(2)56(37(3)4)63(61-31-13-29-53)62-35-38(14-11-12-30-54-50-46-27-21-42(52)32-49(46)55-48-28-26-45(59-7)33-47(48)50)34-60-51(39-15-9-8-10-16-39,40-17-22-43(57-5)23-18-40)41-19-24-44(58-6)25-20-41/h8-10,15-28,32-33,36-38H,11-14,30-31,34-35H2,1-7H3,(H,54,55)

InChIKey

IVSKHMOVPUZDIM-UHFFFAOYSA-N

Solubility

Soluble in Anhydrous Acetonitrile

Storage

Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00543