Name: 5'-POM-(E)-vinyl phosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite
Brand: BOC Sciences
Price: 399 USD
Availability: MadeToOrder

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5'-POM-(E)-vinyl phosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite

5'-POM-(E)-vinyl phosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite

5'-POM-(E)-vinyl phosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite is used in oligonucleotide synthesis. It is employed to introduce modified adenine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Ordering Information

Catalog Number	Size	Price	Stock	Quantity
BRP-00571	250 mg	$399	In stock

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Catalog

BRP-00571

Synonyms

N-[9-[(5E)-6-[Bis[(2,2-dimethyl-1-oxopropoxy)methoxy]phosphinyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5,6-dideoxy-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-9H-purin-6-yl]benzamide; (E)-VP-2'-OMe-A(Bz)-CE-Phosphoramidite; (E)-Vinyl phosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite; 5'-VP-2'-0Me-A(Bz)-CE-Phosphoramidite; (E)-5'-VP-2'-0Me-A(Bz)-CE-Phosphoramidite

CAS

2419895-65-9

IUPAC Name

((((E)-2-((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-4-methoxytetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)

Molecular Weight

889.88

Molecular Formula

C40H57N7O12P2

SMILES

N#CCCOP(OC1C(OC(N2C=NC=3C(=NC=NC32)NC(=O)C=4C=CC=CC4)C1OC)C=CP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)N(C(C)C)C(C)C

InChI

InChI=1S/C40H57N7O12P2/c1-26(2)47(27(3)4)60(55-20-15-19-41)59-31-29(18-21-61(51,56-24-53-37(49)39(5,6)7)57-25-54-38(50)40(8,9)10)58-36(32(31)52-11)46-23-44-30-33(42-22-43-34(30)46)45-35(48)28-16-13-12-14-17-28/h12-14,16-18,21-23,26-27,29,31-32,36H,15,20,24-25H2,1-11H3,(H,42,43,45,48)/b21-18+/t29-,31-,32-,36-,60?/m1/s1

InChIKey

DCUPCJOKPAHCLB-OZKJWBRJSA-N

Purity

≥98%

Storage

Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00571