5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite - CAS 163759-97-5

Catalog number: BRA-026

5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite is a building block for introducing uridine units into oligonucleotides.

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Synonyms

2'-O-MOE-U-3'-phosphoramidite; 5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine-3'-CED-phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-(2-methoxyethyl)uridine

CAS

163759-97-5

IUPAC Name

3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-(2-methoxyethoxy)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

Molecular Weight

804.86

Molecular Formula

C42H53N4O10P

Canonical SMILES

CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCOC)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

InChI

InChI=1S/C42H53N4O10P/c1-29(2)46(30(3)4)57(54-25-11-23-43)56-38-36(55-40(39(38)52-27-26-49-5)45-24-22-37(47)44-41(45)48)28-53-42(31-12-9-8-10-13-31,32-14-18-34(50-6)19-15-32)33-16-20-35(51-7)21-17-33/h8-10,12-22,24,29-30,36,38-40H,11,25-28H2,1-7H3,(H,44,47,48)/t36-,38-,39-,40-,57?/m1/s1

InChIKey

ZLOKLUONKGURQI-UAQIPLLRSA-N

Purity

≥95%

Appearance

White to Off-white Powder

Chemical Structure: