5'-DMT-U-Suc-CPG; 1000 Å (RNA) is a reagent used in the solid-phase synthesis of RNA oligonucleotides for incorporating uridine (U) residues. It features a 5'-DMT (dimethoxytrityl) protective group to protect the 5' end of the uridine base, and a succinyl (Suc) linker that attaches the nucleoside to controlled pore glass (CPG) with a 1000 Å pore size. This setup facilitates efficient incorporation of uridine into RNA sequences while ensuring effective protection and stability during synthesis.
Chemical Structure:
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