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2'-O-C16-rA(Bz)-Phosphoramidite - CAS 2382942-35-8

Catalog number: BRP-00512

2'-O-C16-rA(Bz)-Phosphoramidite

2'-O-C16-rA(Bz)-Phosphoramidite is a specialized reagent utilized in oligonucleotide synthesis. It contains a 2'-O-C16-rA(Bz) modification, where a C16 alkyl chain is attached to the 2'-position of riboadenosine (rA) and a benzoyl (Bz) group is attached to the adenine base. This modification enhances stability and functionality. It facilitates the production of modified RNA oligonucleotides with improved properties, suitable for various molecular biology and biotechnology applications, including RNA interference and gene expression studies.

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Ordering Information
Catalog Number Size Price Stock Quantity
BRP-00512 1 g $599 In stock
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Catalog
BRP-00512
Synonyms
N6-Bz-5'-O-DMTr-2'-O-hexadecanyl adenosine 3'-CED phosphoramidite; DMTr-2'-O-C16-rA(Bz)-3'-CE-Phosphoramidite; 2'-O-C16-A(Bz) phosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-hexadecyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS
2382942-35-8
IUPAC Name
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-hexadecoxyoxolan-2-yl]purin-6-yl]benzamide
Molecular Weight
1098.38
Molecular Formula
C63H84N7O8P
SMILES
CCCCCCCCCCCCCCCCOC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
InChI
InChI=1S/C63H84N7O8P/c1-8-9-10-11-12-13-14-15-16-17-18-19-20-27-42-74-58-57(78-79(76-43-28-41-64)70(47(2)3)48(4)5)55(77-62(58)69-46-67-56-59(65-45-66-60(56)69)68-61(71)49-29-23-21-24-30-49)44-75-63(50-31-25-22-26-32-50,51-33-37-53(72-6)38-34-51)52-35-39-54(73-7)40-36-52/h21-26,29-40,45-48,55,57-58,62H,8-20,27-28,42-44H2,1-7H3,(H,65,66,68,71)/t55-,57-,58-,62-,79?/m1/s1
InChIKey
JEFOGZDZKKCGEJ-OSIIFERKSA-N
Purity
≥95%
Storage
Store at -20 °C

Chemical Structure:

Chemical structure of BRP-00512


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