Olpasiran - CAS 2225856-03-9

Catalog number: BRP-02089

Olpasiran

Olpasiran (AMG890) is a small interfering RNA (siRNA) molecule that significantly reduces the production of Lp(a) in hepatocytes and can be used in studies related to atherosclerotic cardiovascular disease (ASCVD).

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Catalog
BRP-02089
Synonyms
AMG 890; ARC-LPA; AMG-890; AMG890; ARC LPA; RNA, (Cm-sp-Am-Gm-Cm-Cm-Cm-Cm-Um-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)U-Um-Gm-Um-Um-Am-Um-Am-Cm-Gm-(3'→3')-sp-dA), 5'-[O-[(23S,28S)-37-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-23,28-bis[[[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]carbonyl]-21,26,31-trioxo-3,6,9,12,15,18,35-heptaoxa-22,27,32-triazaheptatriacont-1-yl] hydrogen phosphorothioate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)C-sp-Gm-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)U-Am-Am-Cm-Am-Am-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)G-Gm-(2'-deoxy-2'-fluoro)G-Cm-sp-(2'-deoxy-2'-fluoro)U-sp-Gm) (1:1); ARO-LPA
CAS
2225856-03-9
Storage
Store at -20 °C
Sequence
RNA, (cagccccuuauuguuauacga), complex with RNA (ucguauaacaauaaggggcug) (1:1)
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