Name: 2'-tBDSilyl Adenosine (n-PAC) CED phosphoramidite
Brand: BOC Sciences
Price: 598 USD
Availability: MadeToOrder

2'-tBDSilyl Adenosine (n-PAC) CED phosphoramidite

2'-tBDSilyl Adenosine (n-PAC) CED Phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It incorporates a 2'-tert-butyldimethylsilyl (tBDSilyl) group onto the adenosine (A) nucleoside at the 2'-position. Additionally, it features a phenoxyacetyl (Pac) group and a controlled-efficiency (CED) phosphoramidite for efficient incorporation during solid-phase synthesis. This reagent enables the production of modified RNA oligonucleotides with improved stability and functionality, suitable for various molecular biology and biotechnology applications, including RNA interference and gene expression studies.

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Ordering Information

Catalog Number	Size	Price	Stock	Quantity
BRP-00233	1 g	$598	In stock

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Catalog

BRP-00233

Synonyms

PAC-rA CEP; N-blocked-5'-O-DMT-2'-O-TBDMS CED adenosine phosphoramidite; (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-Dimethoxytrityl-N-phenoxyacetyl-Adenosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(phenoxyacetyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Pac-A-CE phosphoramidite; rA (Pac) CE-Phosphoramidite; 2'-TBDMS Adenosine (n-PAC) CED phosphoramidite

CAS

121058-86-4

IUPAC Name

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]-2-phenoxyacetamide

Molecular Weight

1018.22

Molecular Formula

C54H68N7O9PSi

SMILES

CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=NC3=C(N=CN=C32)NC(=O)COC4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

InChI

InChI=1S/C54H68N7O9PSi/c1-37(2)61(38(3)4)71(67-32-18-31-55)69-48-45(33-66-54(39-19-14-12-15-20-39,40-23-27-42(63-8)28-24-40)41-25-29-43(64-9)30-26-41)68-52(49(48)70-72(10,11)53(5,6)7)60-36-58-47-50(56-35-57-51(47)60)59-46(62)34-65-44-21-16-13-17-22-44/h12-17,19-30,35-38,45,48-49,52H,18,32-34H2,1-11H3,(H,56,57,59,62)/t45-,48-,49-,52-,71?/m1/s1

InChIKey

DBCNFFIOULAURJ-NMRDYAFNSA-N

Purity

95%

Chemical Structure: